I have been asked to post the answers to the tut I have given you. The problem with that, is that you will learn the answers and not know how to approach answering these type of questions. Ideally you should be working out the answers, asking me to have a look at it, and then I would help you in knowing how to approach answering the questions. So I am very hesitant in posting answers.
What I will do, is guide you, on how to attempt the questions, and hopefully, help you understand the questions asked. So here goes:
1. Write 2 sentences to show the relationship between TC, CD4, CD8, MHC class II and APC.
NB! Some components are missing
Your answer should include ONLY 2 sentences, and each sentence should explain one relationship. Remember that cells express cell markers, and that cell markers interact with each other. So your answer should go something like this: ---- cell expressing -------- interacts with ------- expressed by -------
Then blanks will either be the cell type of the cell marker.
You already know that Tc expresses CD8, TH expresses CD4, MHC class II is expressed by APC’s and that MHC class I is expressed by nucleated cells.
So your final answer should be:
TC expressing CD8 interacts with MHC class I expressed by nucleated cells
And vice versa……
2. Supply immunologically sound reasons why booster shots of vaccines are necessary.
This questions relates indirectly to the differences between the primary and secondary IR.
Now booster shots of vaccines are the second and subsequent doses of vaccines. We all know that most vaccines are given more than once. A classic example is measles.
A vaccine is an altered version of the antigen that remains antigenic but is no longer pathogenic. So when it is given twice, it will induce a secondary IR. We know that more Ab are produced in the secondary IR and the Ab produced have a greater affinity. Surely these are good attributes to have. Yes indeed, I want those AB!!!
These are the only questions I expect you to have a problem with. Please see me if you need further help.
