We have learnt that TH cells express CD4 which interacts with MHC class II expressed by APC's.
There are other co receptors involved in the above interaction.
TH cell -------------- APC
LFA-2 LFA-3
LFA-1 ICAM-1
CD28 B7
TCR+CD4 MHC class II + peptide
The most important interaction is between CD28 and B7
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