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This blog was designed for the Biomedical Technology students at the Durban University of Technology, in Durban, South Africa. It consists of short notes on aspects that I feel that my students grapple with, and aims to provide a better explanation than that they would receive in lectures. It is also a very personal blog, where I feel comfortable 'talking' to my students.

Please email me sherlien@dut.ac.za




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Tuesday, August 2, 2011

APC's

So how many of you read Victorian novels/romances? Yeah I suppose not many of you are readers, right??? Okay so have any of you watched a like really old movie like Gone with the Wind? where debutantes were presented to society as having learnt all the social graces and are ready for marriage. Obviously all the eligible (rich and handsome helps here) bachelors were invited to these occasions. Rather like a cattle sale, I think..... women for sale (marriage) and men (buyers) on the lookout for the best. Sp how far have we come in South Africa with our interpretation of the debs ball??????
These women were presented and the bill paid by rich relatives, usually old dowager ladies.
So anyway the point I am trying to make here:
APC's (Ag presenting cells) are rather like these old ladies. They present Ag to immune cells (or the immune system) for processing. In most cases ( we will do exceptions later on), Ag will not stimulate an immune response without an APC. Now and APC is not a particular type of cell, but rather a function carried out be specific cells. B cells, monocytes, macrophages, phagocytes, neutrophils, dendritic cells all act as APC's.

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