Chempath test 2

1. State whether the following statements are true or false. If false, correct the statement. [½ mark for True or False – 1 mark for an explanation of the incorrect statement]

In a work flow system, input refers to specimens, request forms and reagents.
For critical care patients, specimens are collected less frequently.
PTH is present in skin and from diet.
One of the causes of hyperphoshatemia is hypothyroidism.
EGTA binds to Mg so that one can measure the calcium content in the patient’s sample.
Aldosterone is antagonistic in that it increases serum Mg by promoting excretion by kidney.
Iron transport is via transferrin where each molecule binds two Fe 2+ ions.
A fetal lung maturity is when the LSAR may be 1.5, PG positive.

[10]
2. Calculate the recovery of the following Fe sample.

Sample 1: 1.0 ml serum + 0.2 ml H2O
Sample 2: 1.0 ml serum + 0.2 ml 10 µmol/l standard

Concentration:
Fe measured
Sample 1 31.0 µmol/l
Sample 2 32.5 µmol/l

[9]


3. Compare diagrams of LSAR in patients with lung maturity and lung immaturity. [6]
4. Write all the precautions of the globulin test for CSF measurement. [4]

5. Compare the laboratory findings of a patient with an exudate to that of another patient with a transudate effusion.
[9]

6. Explain all the factors to be taken when iron is measured. [8]

7. A 21 female with dizzy spells went the local clinic as this was affecting her work at the factory where she was employed. The doctor examined her and had blood samples taken and were sent to the laboratory. A report from the new automated analyser showed the following:

Serum iron: 0.007 mmol/l

7.1 Predict the doctor’s diagnosis based on the result obtained. [3]
7.2 Select the tests that may be done on the above patient. [3]
7.3 Comment on the units of the result. [1]

8. Make recommendations of how space could be best utilized when designing a laboratory. [10]

9. Determine the molarity of a bottle of glacial acetic acid, which has a specific gravity of 1.046 g/ml and a percent assay of 99.2%. [5]


10. A report on a male patient read as follows:
Calcium : 2.25 mmol/l
Phosphate : 0.90 mmol/l
Magnesium : 0.51 mmol/l

10.1 Explain the above results and give the possible diagnosis. [Give reasons for the abnormal result(s)] [7]

10.2 What would the treatment be for the above patient? [1]


[Additional Information: Mass C = 12 H =1 O =12]